InnovoSIL TM-1 Antimicrobial Silver Works Against Candida auris and Superbugs
Edmonton, AB - TheNewswire - May 15, 2023 - Innovotech Inc. (TSX-V:IOT) reports that its InnovoSIL™-1 silver periodate antimicrobial compound acts as an excellent antimicrobial against Candida auris.
C. auris is an emerging fungus (yeast) causing a serious global health threat due to its resistance to antibiotic treatments and its tendency to cause severe illness in people with weakened immune systems. C. auris infections have been associated with 30-60% mortality rates in hospitalized patients.
Coated onto a wound dressing model, InnovoSIL™-1 silver prevented a broad spectrum of microorganisms from adhering to the dressing surface over time under clinically relevant conditions, while eliminating surrounding planktonic (free-floating) microorganisms. Other organisms tested included superbugs well-known for causing difficult-to-treat infections that tend to spread rapidly in healthcare settings: Methicillin-Resistant Staphylococcus aureus (MRSA), Vancomycin-Resistant Enterococcus faecalis (VRE), Coagulase Negative Staphylococcus epidermidis (CONS), and Acinetobacter baumannii.
The evaluation was performed using Innovotech’s proprietary BEST Assay™ testing system, which is included in its scope of accreditation under ISO 17025:2017.
About InnovoSIL™-1 Antimicrobial Silver
InnovoSIL™-1 antimicrobial silver possesses exceptional properties for efficacy against microbial biofilms as well as simplicity for coating onto or incorporating into medical devices, with favorable release characteristics. The unique structure around the silver present in the anion slows its inactivation by bodily fluids. Combining silver and iodine increases antimicrobial mechanisms of action, reducing the likelihood of a target developing resistance to it. InnovoSIL™-1 antimicrobial silver has demonstrated excellent stability under a wide variety of challenges and can be easily synthesized with high purity in a form that is simple to deposit onto metals or incorporate into wound dressings, gels, or polymers. Innovotech is presently working with a number of industry collaborators who are pursuing a variety of applications for InnovoSIL™-1 antimicrobial silver.
Innovotech is a Canadian biotechnology company owning proprietary intellectual property, conducting contract research, and owning and providing proprietary devices for testing in multiple applications in microbiology. Innovotech can be found online at www.innovotech.ca.
Dr. Patricia Nadworny, Ph.D, B.Sc, P.Eng
Chief Scientific Officer and Quality & Safety Director
780-448-0585 ext. 7
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